| Date | Location | Result | |
| 02/21/50 | Sherman, Texas | Midwestern State 58, Austin College 50 | Box score |
| 02/17/50 | Wichita Falls, Texas (Hardin Gym) | Houston 68, Midwestern State 40 | Box score |
| 02/14/50 | Wichita Falls, Texas | Midwestern State 43, Trinity (Texas) 40 | Box score |
| 02/10/50 | Wichita Falls, Texas (Hardin Gym) | Midwestern State 60, Wayland Baptist 45 | Box score |
| 02/07/50 | Wichita Falls, Texas (Hardin Gym) | Midwestern State 60, Austin College 42 | Box score |
| 02/04/50 | Denton, Texas | North Texas 61, Midwestern State 52 | Box score |
| 01/31/50 | Wichita Falls, Texas (Hardin Gym) | Midwestern State 59, Brooke Army Medical Center 45 | Box score |
| 01/28/50 | Plainview, Texas | Wayland Baptist 81, Midwestern State 57 | Box score |
| 01/26/50 | Commerce, Texas | Texas A&M-Commerce 46, Midwestern State 38 | Box score |
| 01/21/50 | Wichita Falls, Texas (Hardin Gym) | Midwestern State 48, Texas A&M-Commerce 43 | Box score |
| 01/13/50 | San Antonio, Texas | Midwestern State 60, Brooke Army Medical Center 50 | Box score |
| 01/10/50 | San Antonio, Texas | Trinity (Texas) 66, Midwestern State 53 | Box score |
| 01/07/50 | Houston, Texas | Houston 63, Midwestern State 38 | Box score |
| 01/05/50 | Wichita Falls, Texas (Hardin Gym) | Midwestern State 39, North Texas 38 | Box score |
| 01/03/50 | Wichita Falls, Texas (Hardin Gym) | Midwestern State 53, East Texas Baptist 45 | Box score |
| 12/16/49 | Fort Worth, Texas (Birdville Gym) | Texas Wesleyan 66, Midwestern State 52 | Box score |
| 12/13/49 | Wichita Falls, Texas (Hardin Gym) | Haliburton 70, Midwestern State 50 | Box score |
| 12/12/49 | Duncan, Okla. | Haliburton 55, Midwestern State 37 | Box score |
| 12/08/49 | Wichita Falls, Texas (Hardin Gym) | Texas Wesleyan 56, Midwestern State 53 | Box score |
| 11/29/49 | Wichita Falls, Texas (Hardin Gym) | East Texas Baptist 52, Midwestern State 45 | Box score |