| Date | Location | Result | |
| 03/08/60 | Kansas City, Mo. | Tennessee State 102, Midwestern State 83 | Box score |
| 03/03/60 | Wichita Falls, Texas | Midwestern State 81, Texas A&M Corpus Christi 58 | Box score |
| 02/27/60 | Abilene, Texas | Abilene Christian 99, Midwestern State 76 | Box score |
| 02/25/60 | Plainview, Texas | Midwestern State 66, Wayland Baptist 58 | Box score |
| 02/19/60 | Marshall, Texas | Midwestern State 65, East Texas Baptist 51 | Box score |
| 02/17/60 | Wichita Falls, Texas | Midwestern State 85, McMurry 76 | Box score |
| 02/13/60 | Wichita Falls, Texas | Wayland Baptist 64, Midwestern State 61 | Box score |
| 02/09/60 | Sherman, Texas | Midwestern State 60, Austin College 50 | Box score |
| 02/06/60 | Wichita Falls, Texas | Midwestern State 96, Texas Luthuren 60 | Box score |
| 02/05/60 | Wichita Falls, Texas | Texas Wesleyan 90, Midwestern State 79 | Box score |
| 02/01/60 | Wichita Falls, Texas | Midwestern State 88, Abilene Christian 82 | Box score |
| 01/29/60 | Wichita Falls, Texas | East Texas Baptist 72, Midwestern State 64 | Box score |
| 01/23/60 | Wichita Falls, Texas | Midwestern State 83, Austin College 58 | Box score |
| 01/16/60 | Arlington, Texas | Midwestern State 97, Texas Arlington 78 | Box score |
| 01/15/60 | Commerce, Texas | Texas A&M-Commerce 51, Midwestern State 49 | Box score |
| 01/11/60 | Wichita Falls, Texas | Midwestern State 86, St. Edwards 73 | Box score |
| 01/09/60 | Abilene, Texas | Midwestern State 76, McMurry 73 | Box score |
| 01/06/60 | Wichita Falls, Texas | Hardin Simmons 72, Midwestern State 58 | Box score |
| 12/30/59 | Dallas, Texas | Wayland Baptist 38, Midwestern State 32 | Box score |
| 12/29/59 | Dallas, Texas | Texas A&M-Commerce 67, Midwestern State 63 | Box score |
| 12/28/59 | Dallas, Texas | Midwestern State 68, Texas-Pan American 65 | Box score |
| 12/18/59 | Wichita Falls, Texas | Midwestern State 87, Texas Arlington 74 | Box score |
| 12/15/59 | Seguin, Texas | Texas Luthuren 81, Midwestern State 72 | Box score |
| 12/14/59 | Austin, Texas | Midwestern State 81, St. Edwards 77 | Box score |
| 12/11/59 | College Station, Texas | Texas A&M 70, Midwestern State 43 | Box score |
| 12/09/59 | Canyon, Texas | West Texas A&M 74, Midwestern State 67 | Box score |
| 12/07/59 | Wichita Falls, Texas | Midwestern State 70, Texas A&M-Commerce 67 | Box score |
| 12/03/59 | Wichita Falls, Texas | West Texas A&M 85, Midwestern State 84 | Box score |
| 12/01/59 | Abilene, Texas | Midwestern State 90, Hardin Simmons 84 | Box score |
| 11/28/59 | Durant, Okla. | Southeastern Oklahoma 40, Midwestern State 35 | Box score |
| 11/27/59 | Durant, Okla. | Midwestern State 80, Delta State 66 | Box score |
| 11/23/59 | Weatherford, Okla. | Southwestern Oklahoma 70, Midwestern State 65 | Box score |
| 11/19/59 | Wichita Falls, Texas | Midwestern State 87, Southwestern Oklahoma 59 | Box score |