| Date | Location | Result | |
| 03/09/66 | Kansas City, Mo. | Illinois Wesleyan 96, Midwestern State 82 | Box score |
| 03/08/66 | Kansas City, Mo. | Midwestern State 94, Monmouth 92 | Box score |
| 02/28/66 | Wichita Falls, Texas | Midwestern State 84, Texas-Pan American 75 | Box score |
| 02/26/66 | Edinburg, Texas | Midwestern State 81, Texas-Pan American 77 | Box score |
| 02/24/66 | Wichita Falls, Texas | Midwestern State 93, Wayland Baptist 63 | Box score |
| 02/21/66 | Beaumont, Texas | Lamar 98, Midwestern State 96 | Box score |
| 02/19/66 | Wichita Falls, Texas | Midwestern State 89, Austin College 72 | Box score |
| 02/14/66 | Wichita Falls, Texas | Midwestern State 9, LeTourneau 8 | Box score |
| 02/12/66 | Plainview, Texas | Midwestern State 62, Wayland Baptist 61 | Box score |
| 02/09/66 | Wichita Falls, Texas | Midwestern State 131, Bishop College 77 | Box score |
| 02/05/66 | Sherman, Texas | Midwestern State 61, Austin College 46 | Box score |
| 02/02/66 | Dallas, Texas | Midwestern State 92, Bishop College 67 | Box score |
| 01/31/66 | San Angelo, Texas | Angelo State 103, Midwestern State 92 | Box score |
| 01/27/66 | Bethany, Okla. | Midwestern State 94, Oklahoma Christian 71 | Box score |
| 01/22/66 | Wichita Falls, Texas | Midwestern State 86, Angelo State 70 | Box score |
| 01/15/66 | Lubbock, Texas | Texas Tech 102, Midwestern State 88 | Box score |
| 01/12/66 | Wichita Falls, Texas | Midwestern State 100, Tarleton State 54 | Box score |
| 01/06/66 | Longview, Texas | Midwestern State 82, LeTourneau 56 | Box score |
| 01/05/66 | Huntsville, Texas | Sam Houston State 102, Midwestern State 84 | Box score |
| 12/30/65 | Dallas, Texas | Midwestern State 82, Sam Houston State 67 | Box score |
| 12/29/65 | Dallas, Texas | Midwestern State 89, Texas-Arlington 74 | Box score |
| 12/29/65 | Dallas, Texas | Midwestern State 92, Texas Wesleyan 65 | Box score |
| 12/18/65 | Wichita Falls, Texas | Midwestern State 76, Lamar 72 | Box score |
| 12/16/65 | Abilene, Texas | Midwestern State 94, McMurry 77 | Box score |
| 12/13/65 | Wichita Falls, Texas | Midwestern State 92, Oklahoma Christian 77 | Box score |
| 12/11/65 | Fort Worth, Texas | Sul Ross State 89, Midwestern State 87 | Box score |
| 12/10/65 | Fort Worth, Texas | Midwestern State 76, Lamar 71 | Box score |
| 12/07/65 | Stephenville, Texas | Midwestern State 91, Tarleton State 78 | Box score |
| 12/04/65 | Wichita Falls, Texas | Sam Houston State 87, Midwestern State 80 | Box score |
| 12/01/65 | Albuquerque, N.M. | New Mexico 95, Midwestern State 58 | Box score |
| 11/29/65 | Wichita Falls, Texas | Midwestern State 79, McMurry 68 | Box score |
| 11/22/65 | Wichita Falls, Texas | Midwestern State 98, Stephen F. Austin 84 | Box score |