| Date | Location | Result | |
| 03/24/10 | Springfield, Mass. | St. Cloud State (Minn.) 92, Midwestern State 88 | Box score |
| 03/16/10 | Wichita Falls, Texas | Midwestern State 60, Central Missouri 59 | Box score |
| 03/14/10 | Wichita Falls, Texas | Midwestern State 71, Tarleton State 56 | Box score |
| 03/13/10 | Wichita Falls, Texas | Midwestern State 91, Incarnate Word 74 | Box score |
| 03/06/10 | Bartlesville, Okla. | Midwestern State 65, Tarleton State 55 | Box score |
| 03/05/10 | Bartlesville, Okla. | Midwestern State 74, Northeastern State 64 | Box score |
| 03/03/10 | Bartlesville, Okla. | Midwestern State 77, Southwestern Okla. 65 | Box score |
| 02/24/10 | Wichita Falls, Texas | Midwestern State 105, Angelo State 100 | Box score |
| 02/20/10 | Wichita Falls, Texas | Midwestern State 96, Abilene Christian 83 | Box score |
| 02/17/10 | Kingsville, Texas | Midwestern State 87, Texas A&M-Kingsville 74 | Box score |
| 02/13/10 | Wichita Falls, Texas | Midwestern State 76, Eastern New Mexico 57 | Box score |
| 02/10/10 | Canyon, Texas | West Texas A&M 68, Midwestern State 58 | Box score |
| 02/06/10 | Wichita Falls, Texas | Midwestern State 72, Tarleton State 69 | Box score |
| 02/03/10 | Stephenville, Texas | Midwestern State 66, Tarleton State 49 | Box score |
| 01/30/10 | Abilene, Texas | Midwestern State 78, Abilene Christian 77 | Box score |
| 01/27/10 | Wichita Falls, Texas | Midwestern State 85, Texas A&M-Kingsville 66 | Box score |
| 01/25/10 | Wichita Falls, Texas | Midwestern State 78, Northeastern State 76 | Box score |
| 01/23/10 | Portales, NM | Midwestern State 66, Eastern New Mexico 59 | Box score |
| 01/20/10 | Wichita Falls, Texas | Midwestern State 90, West Texas A&M 69 | Box score |
| 01/13/10 | San Angelo, Texas | Angelo State 84, Midwestern State 76 | Box score |
| 01/07/10 | Commerce, Texas | Midwestern State 90, Texas A&M-Commerce 86 | Box score |
| 01/02/10 | Wichita Falls, Texas | Midwestern State 98, Dallas Christian (Texas) 57 | Box score |
| 12/21/09 | Wichita Falls, Texas | Midwestern State 89, Southwestern Okla. 70 | Box score |
| 12/19/09 | Wichita Falls, Texas | Midwestern State 86, Cameron 83 | Box score |
| 12/14/09 | Ada, Okla. | Midwestern State 103, East Central 85 | Box score |
| 12/12/09 | Durant, Okla. | Midwestern State 72, Southeastern Okla. 42 | Box score |
| 12/03/09 | Wichita Falls, Texas | Midwestern State 96, Central Oklahoma 89 | Box score |
| 11/30/09 | Wichita Falls, Texas | Midwestern State 97, Jarvis Christian 64 | Box score |
| 11/28/09 | San Antonio, Texas | Midwestern State 89, St. Mary's (Texas) 71 | Box score |
| 11/27/09 | San Antonio, Texas | Midwestern State 74, Langston (Okla.) 56 | Box score |
| 11/21/09 | Wichita, Kan. | Midwestern State 72, Newman (Kan.) 65 | Box score |
| 11/18/09 | Wichita Falls, Texas | Midwestern State 83, St. Mary's (Texas) 72 | Box score |
| 11/16/09 | Austin, Texas | Midwestern State 76, St. Edward's (Texas) 61 | Box score |
| 11/15/09 | Austin, Texas | Midwestern State 63, Trinity (Texas) 52 | Box score |