| Date | Location | Result | |
| Apr 30, 2022 | Wichita Falls, Texas | Texas Woman's 6, Midwestern State 0 | Box score |
| Apr 30, 2022 | Wichita Falls, Texas | Texas Woman's 2, Midwestern State 1 | Box score |
| Apr 23, 2022 | Wichita Falls, Texas | Tex. A&M Int'l 7, Midwestern State 5 | Box score |
| Apr 23, 2022 | Wichita Falls, Texas | Midwestern State 10, Tex. A&M Int'l 7 | Box score |
| Apr 22, 2022 | Wichita Falls, Texas | Tex. A&M-Kingsville 12, Midwestern State 5 | Box score |
| Apr 22, 2022 | Wichita Falls, Texas | Tex. A&M-Kingsville 12, Midwestern State 1 | Box score |
| Apr 10, 2022 | Portales, N.M. | Midwestern State 11, Eastern NM 1 | Box score |
| Apr 10, 2022 | Portales, N.M. | Eastern NM 8, Midwestern State 7 | Box score |
| Apr 08, 2022 | Canyon, Texas | West Tex. A&M 7, Midwestern State 6 | Box score |
| Apr 08, 2022 | Canyon, Texas | West Tex. A&M 15, Midwestern State 7 | Box score |
| Apr 03, 2022 | Wichita Falls, Texas | Lubbock Christian 5, Midwestern State 4 | Box score |
| Apr 03, 2022 | Wichita Falls, Texas | Lubbock Christian 11, Midwestern State 2 | Box score |
| Apr 01, 2022 | Wichita Falls, Texas | Angelo State 4, Midwestern State 2 | Box score |
| Apr 01, 2022 | Wichita Falls, Texas | Angelo State 11, Midwestern State 5 | Box score |
| Mar 27, 2022 | Lawton, Okla. | Midwestern State 5, Cameron 4 | Box score |
| Mar 27, 2022 | Lawton, Okla. | Cameron 8, Midwestern State 0 | Box score |
| Mar 25, 2022 | Oklahoma City, Okla. | Okla. Christian 5, Midwestern State 0 | Box score |
| Mar 25, 2022 | Oklahoma City, Okla. | Okla. Christian 9, Midwestern State 1 | Box score |
| Mar 20, 2022 | Wichita Falls, Texas | Texas-Tyler 10, Midwestern State 1 | Box score |
| Mar 20, 2022 | Wichita Falls, Texas | Texas-Tyler 15, Midwestern State 5 | Box score |
| Mar 18, 2022 | Wichita Falls, Texas | Tex. A&M-Commerce 1, Midwestern State 0 | Box score |
| Mar 18, 2022 | Wichita Falls, Texas | Tex. A&M-Commerce 4, Midwestern State 1 | Box score |
| Mar 15, 2022 | Wichita Falls, Texas | Embry-Riddle (FL) 6, Midwestern State 5 | Box score |
| Mar 15, 2022 | Wichita Falls, Texas | Embry-Riddle (FL) 10, Midwestern State 2 | Box score |
| Mar 14, 2022 | Wichita Falls, Texas | Midwestern State 2, St. Edward's 1 | Box score |
| Mar 14, 2022 | Wichita Falls, Texas | Midwestern State 8, St. Edward's 5 | Box score |
| Mar 12, 2022 | Wichita Falls, Texas | St. Mary's 10, Midwestern State 1 | Box score |
| Mar 12, 2022 | Wichita Falls, Texas | St. Mary's 10, Midwestern State 6 | Box score |
| Mar 06, 2022 | Silver City, NM | Western NM 12, Midwestern State 10 | Box score |
| Mar 06, 2022 | Silver City, NM | Midwestern State 16, Western NM 5 | Box score |
| Mar 04, 2022 | Odessa, Texas | Midwestern State 8, Tex. Permian Basin 2 | Box score |
| Mar 04, 2022 | Odessa, Texas | Tex. Permian Basin 3, Midwestern State 2 | Box score |
| Mar 02, 2022 | Wichita Falls, Texas | Central Okla. 4, Midwestern State 2 | Box score |
| Mar 02, 2022 | Wichita Falls, Texas | Central Okla. 6, Midwestern State 5 | Box score |
| Feb 27, 2022 | Tahlequah, Okla. | Northeastern St. 8, Midwestern State 5 | Box score |
| Feb 27, 2022 | Tahlequah, Okla. | Northeastern St. 10, Midwestern State 2 | Box score |
| Feb 20, 2022 | Arkadelphia, Ark. | Tex. A&M-Kingsville 11, Midwestern State 0 | Box score |
| Feb 20, 2022 | Arkadelphia, Ark. | Henderson State 5, Midwestern State 0 | Box score |
| Feb 19, 2022 | Arkadelphia, Ark. | Christian Brothers 4, Midwestern State 3 | Box score |
| Feb 19, 2022 | Arkadelphia, Ark. | Ouachita Baptist 2, Midwestern State 1 | Box score |
| Feb 13, 2022 | Edmond, Okla. | Rogers St. 4, Midwestern State 3 | Box score |
| Feb 12, 2022 | Edmond, Okla. | Fort Hays St. 5, Midwestern State 4 | Box score |
| Feb 12, 2022 | Oklahoma City, Okla. | Midwestern State 11, Southwestern Okla. 1 | Box score |
| Feb 11, 2022 | Edmond, Okla. | Central Okla. 9, Midwestern State 0 | Box score |
| Feb 11, 2022 | Oklahoma City, Okla. | Mo. Southern St. 17, Midwestern State 8 | Box score |