| Date | Location | Result | |
| Nov 11, 2010 | Canyon, Texas | Tarleton State 3, Midwestern State 2 (25-10,21-25,21-25,25-16,16-14) | Box score |
| Nov 04, 2010 | Wichita Falls, Texas | Midwestern State 3, Tarleton State 1 (25-10,20-25,25-19,25-22) | Box score |
| Nov 02, 2010 | Lawton, Okla. | Midwestern State 3, Cameron 1 (25-19,20-25,25-15,25-18) | Box score |
| Oct 30, 2010 | Wichita Falls, Texas | Midwestern State 3, Central Okla. 1 (24-26,25-23,25-19,25-20) | Box score |
| Oct 28, 2010 | Wichita Falls, Texas | Southwestern Okla. 3, Midwestern State 2 (16-25,25-18,27-25,7-25,15-13) | Box score |
| Oct 26, 2010 | Plainview, Texas | Wayland Baptist 3, Midwestern State 1 (25-15,11-25,25-21,25-21) | Box score |
| Oct 23, 2010 | Denton, Texas | Midwestern State 3, Texas Woman's 1 (25-21,18-25,25-18,25-19) | Box score |
| Oct 21, 2010 | Commerce, Texas | Midwestern State 3, Texas A&M-Commerce 1 (25-22,25-11,23-25,25-16) | Box score |
| Oct 18, 2010 | Lubbock, Texas | Lubbock Christian 3, Midwestern State 0 (25-19,25-23,25-11) | Box score |
| Oct 16, 2010 | Wichita Falls, Texas | Angelo State 3, Midwestern State 0 (25-21,25-17,25-23) | Box score |
| Oct 14, 2010 | Wichita Falls, Texas | Abilene Christian 3, Midwestern State 2 (18-25,22-25,28-26,25-22,15-13) | Box score |
| Oct 09, 2010 | Canyon, Texas | West Texas A&M 3, Midwestern State 0 (26-24,25-22,25-22) | Box score |
| Oct 07, 2010 | Portales, NM | Midwestern State 3, Eastern New Mexico 1 (25-13,14-25,25-16,25-20) | Box score |
| Oct 02, 2010 | Durant, Okla. | Oklahoma Baptist 3, Midwestern State 1 (17-25,26-24,25-17,25-16) | Box score |
| Oct 02, 2010 | Durant, Okla. | Midwestern State 3, St. Mary's 0 (25-20,25-22,25-23) | Box score |
| Sep 25, 2010 | Wichita Falls, Texas | Midwestern State 3, Texas A&M-Kingsville 0 (25-22,25-20,25-21) | Box score |
| Sep 23, 2010 | Wichita Falls, Texas | Midwestern State 3, Incarnate Word 1 (25-14,23-25,25-20,26-24) | Box score |
| Sep 21, 2010 | Wichita Falls, Texas | Dallas Baptist 3, Midwestern State 1 (25-22,18-25,25-16,25-21) | Box score |
| Sep 18, 2010 | Ada, Okla. | East Central 3, Midwestern State 1 (26-24,25-20,16-25,29-27) | Box score |
| Sep 16, 2010 | Durant, Okla. | Midwestern State 3, Southeastern Okla. 0 (25-17,26-24,25-21) | Box score |
| Sep 15, 2010 | Wichita Falls, Texas | Midwestern State 3, Okla. Panhandle St. 0 (25-8,25-15,25-22) | Box score |
| Sep 11, 2010 | Stephenville, Texas | Midwestern State 3, St. Mary's 2 (16-25,23-25,25-10,25-18,15-6) | Box score |
| Sep 11, 2010 | Stephenville, Texas | Midwestern State 3, UT-Permian Basin 1 (25-18,25-20,29-31,25-17) | Box score |
| Sep 10, 2010 | Stephenville, Texas | Southwest Baptist 3, Midwestern State 2 (25-9,19-25,23-25,27-25,16-14) | Box score |
| Sep 07, 2010 | Dallas, Texas | Midwestern State 3, Dallas Baptist 1 (25-14,20-25,25-21,25-18) | Box score |
| Sep 04, 2010 | Omaha, Neb. | Emporia State 3, Midwestern State 2 (25-15,15-25,18-25,25-20,15-7) | Box score |
| Sep 04, 2010 | Omaha, Neb. | Nebraska-Omaha 3, Midwestern State 0 (25-21,25-20,25-22) | Box score |
| Sep 03, 2010 | Omaha, Neb. | Northwest Missouri 3, Midwestern State 0 (25-22,25-21,25-22) | Box score |
| Sep 03, 2010 | Omaha, Neb. | Midwestern State 3, Chadron State 0 (25-11,25-17,25-11) | Box score |